R. Loch Macdonald, MD, PhD, Chief Scientific Officer

Dr. Macdonald is currently Keenan Endowed Chair, Head, Division of Neurosurgery at St. Michael’s Hospital and Professor of Neurosurgery at the University of Toronto. He is a scientist, researcher and neurosurgeon and a recognized expert on brain hemorrhage, including delayed cerebral ischemia (DCI). For the past 20 years, his research interest has focused on improving patient outcome after brain hemorrhage, with a specific focus on developing a cure for cerebral vasospasm and DCI. He, along with Dr. Bryce Weir, has authored one of the definitive textbooks on cerebral vasospasm, Cerebral Vasospasm (2001 Academic Press), which is used in medical schools throughout the world. He has published over 400 articles, authored multiple textbooks, and has spoken at many international conferences on the topic of cerebral vasospasm and DCI. Dr. Macdonald’s publications have been sited thousands of times.

Recently Dr. Macdonald was an author of the American Heart / American Stroke Association Guidelines on the management of intracerebral hemorrhage. Dr. Macdonald was also a member of the CONSCIOUS-1, -2 and -3 Steering Committees that were prospective, multi-center, blinded, randomized, placebo-controlled, clinical trials studying clazosentan in patients with aneurysmal subarachnoid hemorrhage.

Prior to becoming Chair at St. Michael’s Hospital, Dr. Macdonald was Professor of Surgery and Radiation & Cellular Oncology at the University of Chicago Medical Center. Dr. Macdonald completed medical school at the University of British Columbia, Vancouver, British Columbia, Canada and completed his Ph.D., (Experimental Surgery), at the University of Alberta, Edmonton, Alberta, Canada, under the guidance of Dr. Bryce Weir. Following his Ph.D. Dr. Macdonald completed his Neurosurgery residency at the University of Toronto, Toronto, Ontario, Canada.